久久亚洲国产成人影院-久久亚洲国产的中文-久久亚洲国产高清-久久亚洲国产精品-亚洲图片偷拍自拍-亚洲图色视频

Global EditionASIA 中文雙語(yǔ)Fran?ais
China
Home / China / Delegates

Scientific researcher driven by passion for discovery

By LIN SHUJUAN in Shanghai | China Daily | Updated: 2022-10-13 07:24
Share
Share - WeChat
Chen Lingling talks with students in August at the State Key Laboratory of Molecular Biology at the Chinese Academy of Sciences' Shanghai Institute of Biochemistry and Cell Biology. JIN LIWANG/XINHUA

Chen Lingling is a prolific scientist who works on non-coding RNA, a field in which she is considered a leading expert on the world stage.

After studying biology and pharmacology in Lanzhou, Gansu province, and Shanghai, Chen did her PhD work at the University of Connecticut Health Center in the United States, where she developed an interest in the function of non-coding RNAs.

Ribonucleic acid, or RNA, is a nucleic acid present in all living cells that has structural similarities to DNA. A non-coding RNA is a functional RNA molecule that is transcribed from DNA but not translated into proteins.

Chen returned to Shanghai in 2011 and became one of the first scientists in China dedicated to the research of non-coding RNAs. Today, the 44-year-old scientist, who was elected as a delegate to the upcoming 20th National Congress of the Communist Party of China, is associate director of the State Key Laboratory of Molecular Biology at the Chinese Academy of Sciences' Shanghai Institute of Biochemistry and Cell Biology.

Over the past decade, Chen's lab has made many discoveries related to non-coding RNAs, which account for 98 percent of the transcript sequences in the genome — the complete set of genes or genetic material present in a cell or organism — yet remain little known. Therefore, they are described as the "dark matter" of the micro-universe of life.

For her contributions to the field, Chen has been given numerous honors and awards, including the Howard Hughes Medical Institute International Research Scholar in 2017 and the CAS' Young Investigator Award in 2018.

However, Chen wasn't always sure that research was what she wanted to do. In 2007, when she was halfway through her doctoral studies in biomedicine, she also signed up for a master's degree in business administration.

Chen said that those days of studying for two degrees kept her "crazily fulfilled" and instilled in her a "can-do" attitude. She ultimately chose scientific research over business administration because she was much more intrigued by the human genome.

"The world of RNAs is really interesting. They look the same, like a long chain that can encode genetic information called messenger RNAs (mRNAs), and some others look just like mRNAs but do not encode proteins, thereby acting as non-coding RNAs," Chen said. Her enthusiasm for non-coding RNAs is obvious, as her eyes light up at the very mention of them.

Over the past decade, Chen and her team have discovered new and unusual classes of RNA molecules called long non-coding RNAs, or lncRNAs. Chen's job now is primarily geared toward figuring out how these molecules form, what role they play in gene regulation, and how they may influence disease. She has found that some of these RNAs are conspicuously absent in people with the neurodevelopmental genetic disorder Prader-Willi syndrome.

It is known that Prader-Willi syndrome, a rare genetic defect, is caused by the deletion of a chromosome from the father, "but we don't know what the function of the missing gene segment is," Chen said. "We have learned that this segment is lacking some unusually processed lncRNAs."

Although research on the function of long non-coding RNAs, especially their disease-related function, is still in the early stages, Chen is looking forward to possible new treatments for diseases in the future.

"More and more studies have shown that changes in lncRNA expression levels are closely related to a variety of diseases, including neurological diseases, cardiovascular diseases and cancer," she said.

Over the past decade, Chen has witnessed the vigorous development in the field of long noncoding RNAs and has led her team on a path of rapid development. She described the process as one that is similar to building a business, as it also involves cultivating talent and scouring for funding.

Chen is grateful that she decided to study business administration, because the discipline gave her an opportunity to learn about things outside the laboratory and imbued in her the necessary skills to lead her team.

"Business administration taught me how to plan my time, manage projects and operate teams. I may oversee a laboratory, but it's really no different from running a company," she said.

Even after so many years in this field, Chen said she still feels excited when a scientific hypothesis is proved true. When there is no progress in an experiment for a long time, she doesn't feel discouraged. Instead, she will look for a new direction from the failed experiment.

"Scientific research requires constant exploration. Doesn't 'research' start with 're' (repeat)?" she asked. "Being able to participate in an emerging field itself is a kind of luck. Our understanding of these enigmatic lncRNAs is still far from complete, which is the driving force that motivates me to explore more."

Top
BACK TO THE TOP
English
Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
 
主站蜘蛛池模板: 国产美女一级视频 | 特级a做爰全过程片 | 国产精品久久人人做人人爽 | 成 人 动漫在线观看网站网站 | 久久一级黄色片 | 欧美在线一级精品 | 在线观看免费视频国产 | 欧美成人手机视频免费播放 | 国产女乱淫真高清免费视频 | 手机在线看片福利 | 国产精品久久久久久久久免费 | 日本在线视频不卡 | 欧美人体在线 | 亚洲视频日韩视频 | 成年女人毛片免费视频永久vip | 欧美三级色 | a级毛片免费高清毛片视频 a级毛片免费高清视频 | 欧美69xx| 国产高清成人mv在线观看 | 伊人久热这里只有精品视频99 | 国产一区二区三区免费看 | 日韩a一级欧美一级在线播放 | 玖玖在线国产精品 | a级网站在线观看 | 蕾丝视频永久在线入口香蕉 | 一级a性色生活片久久毛片 一级a做爰片欧欧美毛片4 | 最新国产精品好看的国产精品 | 国产成人a大片大片在线播放 | 欧美成人 综合网播九公社 欧美成人26uuu欧美毛片 | 国产日产亚洲精品 | 国产网红自拍 | 国产三级视频在线播放 | 日韩美女大全视频在线 | 日韩三及片| 国产成人午夜精品影院游乐网 | 久久精品国产亚洲网址 | 一级毛片a免费播放王色 | 久久高清影院 | 艳女伦交一级毛片 | 精品久久久久久中文字幕网 | 亚洲国产精选 |